What is RELION?
RELION (REgularized LIkelihood OptimizatioN) is an open-source program for the refinement of macromolecular structures by single-particle analysis of electron cryomicroscopy (cryo-EM) data
RELION (REgularized LIkelihood OptimizatioN) implements an empirical Bayesian approach for analysis of electron cryo-microscopy (Cryo-EM)
RELION provides refinement methods of singular or multiple 3D reconstructions as well as 2D class averages
RELION is an important tool in the study of living cells
HPC-AI Advisory Council
Performance Analysis Summary
(from Article See RELION – Performance Benchmark and Profiling)
RELION performance testing
- Pool size 4,8,16 gave best performance on 16,24,32 nodes
- SHARP In-Network Computing reduces MPI time by 13% and increase overall application performance by 5
- Performance advantages increases with system size, up to 32 nodes were tested
RELION Profile
- Rank #0 does not perform computation
- Mostly MPI_Barrier (70%)
- Ring communication matrix
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